Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

Hematoxylin and Eosin stained sections from Fine Needle Aspirates (FNAC) samples of HCC patients. HCC patients belonging to different stages (lower stage (a-b) and higher stage (c-d). The photomicrgraphs demonstrates cellular clusters of small cells with enlarged central vein and disorganized architecture (Fig a and b). Figure c and d represents cancer cells in FNAC…

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

Stained Rat liver section observed under foldscope. Panel A shows H&E stained DEN treated rat liver section, with disorganized liver architecture, dilated sinusoids, and expanded portal vein. Panel B shows the same section, with  Oil red-O staining where the positive red staining is more as lipogenic molecules are more active in  this sample. a &...

Oil red O stained Rat liver section –DEN induced hepatocarcinogenesis

Photomicrographs of Oil red O stained Rat liver section –DEN induced hepatocarcinogenesis Figure A  shows DEN treated rat liver sections with  Oil red-O staining which stains lipid fats in tissues. The positive red staining is more as there is more lipogenic molecules. a, b and c are the 2.5X, 3.5X and 4X zoom out images...

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

Hematoxylin and Eosin stained sections from Fine Needle Aspirates (FNAC) samples of HCC patients HCC patients belonging to different stages (of different ages) mainly lower stages. The photomicrgraphs taken with foldscope demonstrates cellular clusters of small cells with enlarged central vein and disorganized architecture with widened trabecular/acinar structures. Figure a and b shows zoom out...

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

Hematoxylin and Eosin stained sections from Fine Needle Aspirates (FNAC) samples of HCC patients The photomicrgraphs taken with foldscope demonstrates higher stages of different HCC patients . Figure A & B represents cancer cells in FNAC samples of different HCC stages patients (of different ages) which shows cellular clusters of small cells with enlarged central...

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

Photomicrographs of H & E stained Rat liver section –DEN  induced hepatocarcinogenesis. Figure A  shows DEN treated rat liver sections. DEN is a potent hepatocarcinogen which helps to produce nodules in liver. The liver architecture is disorganized with dilated sinusoids and expanded portal vein.  Figure B (1.2X) & C (1.4X) are the zoom out images …

Stained Rat liver section observed under foldscope.

Panel A shows H&E stained DEN treated rat liver section, with disorganized liver architecture, dilated sinusoids, and expanded portal vein. Panel B shows the same section, with  Oil red-O staining where the positive red staining is more as lipogenic molecules are more active in  this sample. a & b images are zoom out (3X) images…

Photomicrographs of H & E stained Rat liver section –DEN induced hepatocarcinogenesis after Lithium Chloride treatment

Panel A shows untreated rat liver sections, with normal liver architecture, cuboidal hepatocytes, and radiating hepatic cords surrounding the central vein. Panel B shows DEN treated rat liver sections, with disorganized liver architecture, dilated sinusoids, and expanded portal vein.  Panel C and d,e,f shows post Lithium Chloride treated rat liver sections with cuboidal hepatocytes like…

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

The photomicrgraphs taken with foldscope demonstrates different stages (lower stage (A) and higher stage (B) of HCC patients . Fig A represents cellular clusters of small cells with enlarged central vein and disorganized architecture. Figure B represents cancer cells in FNAC samples of HCC patients with widened trabecular and multilayered cells.  Fig a & b…

Photomicrographs of Oil red O stained Rat liver section

Figure A  shows DEN treated rat liver sections with  Oil red-O staining. The red staining is more as there is more lipogenic molecules.  a is the 1.5X zoom out image of  figure A  and b is the 2.5X zoom out image of figure a.

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

Panel A shows untreated rat liver sections, with normal liver architecture, cuboidal hepatocytes, and radiating hepatic cords surrounding the central vein. Panel B shows DEN treated rat liver sections, with disorganized liver architecture, dilated sinusoids, and expanded portal vein.  Panel C and C(i) shows post Lithium Chloride treated rat liver sections with cuboidal hepatocytes like…

Detecting Hepatitis B virus associated cellular changes in needle aspirate samples of HBV linked Hepatocellular carcinoma patients of different stages

HCC patients belonging to different stages (lower stage (a) and higher stage (b-c). The photomicrgraphs taken with foldscope demonstrates cellular clusters of small cells with enlarged central vein and disorganized architecture with widened trabecular/acinar structures (Fig a and a1). Figure b and c represents cancer cells in FNAC samples of HCC patients with widened trabecular…