Images showing physical instability of solid dispersion

Solid dispersion had a major drawback of converting into crystalline form on long term storage. We prepared solid dispersion of macitentan, and it was stored for 3 months. It showed conversion into crystalline form. The results were confirmed with the help of powder XRD and differential scanning calorimetry analysis. Thus it helps in determining physical…

Solid dispersion of Macitentan

Solid dispersion of macitentan was prepared using solvent evaporation method. The images of freshly prepared solid dispersion was captured using mobile phone one plus 6T, foldscope microscope and LED magnifier. It shows presence of few crystals of irregular and rectangular in shape

The new way for application of foldscope

Earlier, we captured images of tissues and cells of plants, animals and humans. Recently we explored a new way as application of “foldscope in pharmaceuticals”. We used it to study physical characteristics of various drugs. We captured images of macitentan drug. we could determine physical appearance of drug like shape, crystallinity and size with the…