A Giema stained slide from duodenal mucosa. The little dark creatures on top are parasites named Giardia. They can live without oxigen (anaerobic). To move around they have 4 pairs of flagellates. Accorinding to info on wiki Giardia were first described by the Antonie van Leeuwenhoek (a Dutch microscopist) in 1681. The genus is named after Alfred Mathieu Giard (a French zoonologist).


The parasites cause diarrhea, excess gas, stomach or abdominal cramps, upset stomach, and nausea. Giardia infections and is usually associated with poor hygiene and sanitation.F Giardia

7 Comments Add yours

  1. Niramay Gogate says:

    Can you tell me about the big cell like things? Those Giardia are looking great ; but the big blue things are even more fascinating.

  2. Manu Prakash says:

    This is so beautiful. I had seen Giardia; but not in the context of the epithelium. I am assuming the finger like projections are micro-villi from the stomach epithelium; the substrate that the Giardia “stick” to. I also want to point out that how “Giardia” stick to substrates like the epithelium is not understand – they have a little suction disc which is very funny to think about at these length scales.

    Beautiful Image. I want to see more..


  3. laksiyer says:

    Great context. Giardia, key to understanding the origin of eukaryotes. For long they thought it didnt have mitochondria, until they found the mitosome. Giardiasis is not fun though and the treatment with metronidazole is no better.

  4. kbibayoff says:

    Cool! Where did you take a sample of these and what did you use to stain the slide?

    1. aPathite says:

      This is a modified Giemsa. We use it to detect Helicobacter in gastic biopsies.

  5. aPathite says:

    The big blue things are villi from the first section of the small intestines (duodenum).

  6. Good post. I’m going through a few of these issues as well..

Leave a Reply