Plasmodium Falciparum Ringstages – How can I see them more clearly?

I stumbled upon Foldscopes and was interested whether they are really able to detect Malaria. Therefore i bought some Foldscopes as well as malaria parasite samples. However I am not sure if the magnification is enough to clearly detect Malaria and even distinguish different strains.

The best thing i could do was zooming in on my smartphone. This was actually enough to see the ring stages, the pictures were very blurry nonetheless. I also tried using magnification lenses as well as ocular lenses on top of the Foldscope with disappointing results.

If somebody has an idea how i could increase my magnification, please tell me in the comments.

2 Comments Add yours

  1. Manu Prakash says:

    Dear Vergens

    Beautiful picture.

    We make many lenses – and several magnifications higher than 140x (which is the current commercially available foldscope lens). But in the original foldscope paper – we showed many higher magnifications and resolution (350x). See here: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098781

    Foldscope 2.0 which will be released in a few months – will have a higher magnification lens.

    Also – for automation for malaria diagnostics – also see a new platform we have just released. Feel free to write to me at manup@stanford.EDU; if you are interested in field work for malaria.
    https://www.biorxiv.org/content/10.1101/684423v1

    Cheers
    Manu

  2. Jana says:

    Cool.I know alot about Malaria.I never saw malaria under the foldscope. How did you get the samples?

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