Photomicrographs of H & E stained Rat liver section –DEN induced hepatocarcinogenesis after Lithium Chloride treatment . Panel A shows untreated rat liver sections, with normal liver architecture, cuboidal hepatocytes, and radiating hepatic cords surrounding the central vein. Panel B shows DEN treated rat liver sections, with disorganized liver architecture, dilated sinusoids, and expanded portal vein. Panel C and C(i) shows post Lithium Chloride treated rat liver sections with cuboidal hepatocytes like untreated rat liver sections.
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