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<p style="text-align:justify">
 Solid dispersion had a major drawback of converting into crystalline form on long term storage. We  prepared solid dispersion of macitentan, and it was stored for 3 months. It showed conversion into crystalline form.
 <br/>
 The results were confirmed with the help of  powder XRD and differential scanning calorimetry analysis. Thus it helps in determining physical stability of the solid dispersion.
</p>


Images showing physical instability of solid dispersion

Murali Monohar Pandey3 | Tue, May 28, 2019, 10:51 PM

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